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Dilated pupils, or mydriasis: what causes it?

Pupils have the ability to constrict and dilate, as their function is to regulate the amount of light entering the eyeball; however, in some cases, dilation may be caused by an illness or abnormality. What causes dilated pupils?

What is it?

Mydriasis is the dilation of the pupil; this generally occurs when vision is exposed to a low-light environment, triggering what is known as scotopic vision. The pupil is a small opening in the eye that acts as a regulator for the amount of light reaching the retina, adjusting through contractions and dilations. It is entirely covered by the cornea. The muscle fibers that make up the iris change in size, causing the pupil to contract or dilate. This is an automatic process designed to control the amount of light that enters the eyeball. When the pupil contracts, the condition is called miosis. This occurs when the eye is exposed to intense light, activating photopic vision. The circular muscles of the iris—or the iris sphincter—are responsible for pupil contraction, while the radial muscles of the iris are responsible for its dilation.

Causes

Mydriasis, or pupil dilation, can occur for various reasons:
  • Ambient light:

Upon waking, after several hours of sleep, it is normal for the pupils to be dilated—at least until they adjust to daylight or the light in the environment where we find ourselves. Another common situation in which pupils dilate is when we are in dark areas or environments with inadequate lighting where seeing clearly is difficult; the pupils dilate to increase the amount of light entering the eyeball.

It is quite simple: the more light received, the less the pupils dilate; the less exposure to light, the greater the dilation.

  • Emotional stimuli:

Another natural cause of pupil dilation is sudden changes in mood. Emotions such as excitement, nervousness, or enthusiasm can trigger this ocular reaction—regardless of the ambient light level or any other external factors.

  • Chemical agents or drugs:

There are various substances that can also promote pupil dilation.

Some examples include alcohol or drugs, which cause significant stimulation of the muscle fibers that make up the iris. There are also opioid substances that produce the opposite effect—namely, the contraction of the pupil.

  • Diseases:
    • Neurological diseases.

Having a brain tumor or cerebral edema can cause a change in pupil size; the effect may even differ between the two eyes. This can occur, for example, in cases of stroke or hemorrhage.

    • Trigeminal nerve injury.

This nerve controls various parts of the face. When it is affected—for instance, due to a head injury—the pupil may become permanently dilated; this can also lead to paralysis, jaw pain, or migraines.

    • Claude-Bernard-Horner syndrome.

When one pupil contracts, it may create the impression that the other pupil is dilated. An injury to the carotid artery, a lung tumor, or brain damage can trigger this condition, leading to a sunken eye and a drooping eyelid.

    • Symmetric, non-reactive mydriasis.

The pupils remain dilated even when exposed to bright light. When this occurs, it is often an indicator of severe brain damage, such as that seen in cases of cardiorespiratory arrest.

    • Ophthalmological disease.

If pupil dilation is not due to a neurological condition, it may be caused by a structural injury to the eye that compromises ocular health. Possible causes include a tear resulting from a blow, glaucoma, or ischemia of the iris.

Fountain: Oftalvist.es


This information is for informational purposes only. It is in no way a substitute for a diagnosis from a healthcare professional. To obtain medical advice or a diagnosis, please schedule an appointment with a specialist.

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